ll Sedecia, re di Gerusalemme recounts the fate of Zedekiah (Sedecia), king of Jerusalem. He is defeated by Nebukadhnezar (Nabucco), king of Babylon, who opposes him for his alliance with Egypt. He is killed after seeing his son Ismael (Ismaele) die, who intervened in his defence, and, his wife Anna who dies of grief. The protagonist is convinced that he was punished by God for his own idolatry.
After its premiere in 1705 in Urbino, Filippo Ortensio Fabbri considerably reworked the original libretto upon which Alessandro Scarlatti founded his Il Sedecia, re di Gerusalemme. In 1706 a new version premiered which differs from the first by the addition of five arias. This second version was the main source for the Milanese edition edited in 1962 by G. Guarrini.